Transcriptional responses to intermittent hypoxia
نویسندگان
چکیده
منابع مشابه
Physiological and Genomic Consequences of Intermittent Hypoxia Invited Review: Physiological and pathophysiological responses to intermittent hypoxia
Neubauer, Judith A. Invited Review: Physiological and pathophysiological responses to intermittent hypoxia. J Appl Physiol 90: 1593–1599, 2001.—This mini-review summarizes the physiological adaptations to and pathophysiological consequences of intermittent hypoxia with special emphasis given to the pathophysiology associated with obstructive sleep apnea. Intermittent hypoxia is an effective sti...
متن کاملInvited review: Physiological and pathophysiological responses to intermittent hypoxia.
This mini-review summarizes the physiological adaptations to and pathophysiological consequences of intermittent hypoxia with special emphasis given to the pathophysiology associated with obstructive sleep apnea. Intermittent hypoxia is an effective stimulus for evoking the respiratory, cardiovascular, and metabolic adaptations normally associated with continuous chronic hypoxia. These adaptati...
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results results of the current study showed that the minimum inhibitory concentration value of cinnamaldehyde against m. tuberculosis was 200 µg/ml. moreover, rt-pcr data showed that a total of 25 genes were regulated by the cinnamaldehyde. of these, 12 genes were up-regulated, and 13 genes were down-regulated. conclusions cinnamaldehyde is a pattern to expand the new anti-tb drugs, because the...
متن کاملChronic intermittent hypoxia alters ventilatory and metabolic responses to acute hypoxia in rats.
We determined the effects of chronic exposure to intermittent hypoxia (CIH) on chemoreflex control of ventilation in conscious animals. Adult male Sprague-Dawley rats were exposed to CIH [nadir oxygen saturation (SpO2), 75%; 15 events/h; 10 h/day] or normoxia (NORM) for 21 days. We assessed the following responses to acute, graded hypoxia before and after exposures: ventilation (V̇e, via baromet...
متن کاملAltered Metabolic Responses to Intermittent Hypoxia in Mice with Partial Deficiency of Hypoxia-inducible Factor
We have previously shown that exposure of C57BL/6J mice to intermittent hypoxia (IH) leads to: (1) hypertriglyceridemia due to up-regulation of pathways of lipid biosynthesis, including sterol regulatory element binding protein 1 (SREBP-1) and stearoyl CoA desaturase 1 (SCD-1); and (2) hypercholesterolemia due to impaired cholesterol uptake. The goal of the present study was to examine whether ...
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ژورنال
عنوان ژورنال: Respiratory Physiology & Neurobiology
سال: 2008
ISSN: 1569-9048
DOI: 10.1016/j.resp.2008.07.006